drugset / Trial / NCT04197089
Biological Effect of Vitamin D in Patients With Urothelial Carcinoma
Phase 4
Completed
2 enrolled
Germans Trias i Pujol Hospital
Centro Nacional de Investigaciones Oncologicas CARLOS III · collabFundació Institut Germans Trias i Pujol · collabSpanish Clinical Research Network - SCReN · collab
NaSingle-groupOpen-labelTreatment
Summary
The study population will be 50 women or men diagnosed with urothelial cancer candidates to undergo cystectomy as part of their antitumor treatment. The main objective of the study is to determine the biological effect of Vitamin D on tumor tissue phenotype; for thus, all subjects enrolled in the study will take Vitamin D supplementation 4 weeks prior undergoing surgery. Urothelial tissue will be obtained from the surgical procedure and will be studied for the Vitamin D effect on cancer cell, compared with that urothelial tissue biopsy obtained in the moment of cancer diagnosis.
Timeline
- Start
- 2020-02-11
- Primary completion
- 2021-11-22
- Completion
- 2021-11-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Vitamin D | Other / unclassified | 10000 iu | — |
| Subject | Vitamin D | Other / unclassified | 50000 iu | — |