drugset / Trial / NCT04203017

Fecal Microbiota Transplantation After Autologous HSCT in Patients With Multiple Sclerosis

NCT04203017

Phase 1 Terminated 20 enrolled St. Petersburg State Pavlov Medical University
NaSingle-groupOpen-labelTreatment

Summary

The hypothesis of the study is that according to modern data, the pathogenesis of multiple sclerosis is inextricably linked to the patient's microbiota. Therefore, transplantation of a normal fecal microbiota (FMT) can improve the outcome of autologous hematopoietic stem cell transplantation (autoHSCT) by increasing the disease-free period and disease progression suspension for at least 5 years after transplantation, which meets the NEDA (No Evidence of Disease Activity) criteria, satisfying the current trends of clinical neurology.

Timeline

Start
2019-06-01
Primary completion
2023-11-29
Completion
2023-11-29

Drugs

EvaluationDrugModalityDoseRoute
Subject allogeneic fecal microbiota Other / unclassified 30 unknown Oral

Indications