drugset / Trial / NCT04203186
A Clinical Trial to Evaluate Plasmodium Falciparum 7G8 and NF54 Challenge Strains (PfSPZ) in a Head-to-head Comparative Study - (ECG-CHMI)
RandomizedParallel-groupTriple-blindDiagnostic
Summary
A comparison of Malaria events (symptoms and signs of malaria) experienced by subjects infected with PfSPZ Challenge (NF54) vs. PfSPZ Challenge (7G8).
Timeline
- Start
- 2020-03
- Primary completion
- 2021-06
- Completion
- 2021-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Atovaquone | Small molecule | — | — |
| Comparator | Proguanil | Small molecule | — | — |