drugset / Trial / NCT04203641

L-DOS47 Plus Doxorubicin in Advanced Pancreatic Cancer

NCT04203641 ↗

Phase 1/2 Terminated 28 enrolled Helix BioPharma Corporation Theradex · collab
NaSequentialOpen-labelTreatment

Summary

This study will evaluate the safety and tolerability of escalating doses of L-DOS47 in combination with doxorubicin, as well as preliminary anti-tumor activity in patients with previously treated advanced pancreatic cancer.

Timeline

Start
2019-12-11
Primary completion
2024-10-24
Completion
2024-10-24

Outcome

Outcome not reported

Stopped: “The primary reason for early termination was budget constraint.”

Drugs

EvaluationDrugModalityDoseRoute
Subject L-DOS47 Other / unclassified 3 ug/kg —
Subject L-DOS47 Other / unclassified 6 ug/kg —
Subject L-DOS47 Other / unclassified 9 ug/kg —
Background Doxorubicin Other / unclassified 20 mg/m2 Intravenous