drugset / Trial / NCT04204304
Relationship Between Serum Vitamin D Levels and Musculoskeletal Adverse Effects in Patients Using Isotretinoin
Non-randomizedParallel-groupOpen-labelScreening
Summary
Isotretinoin (ISO) has been used in the treatment of patients with severe acne vulgaris (AV) that is resistant to standard therapy with systemic antibiotics and topical agents, over the last few decades. There are various side effects of ISO in the skeletal system. This study investigate the relationship between ISO-induced musculoskeletal adverse effects and serum 25 hydroxy (OH) vitamin D levels in patients with acne vulgaris.
Timeline
- Start
- 2019-03-15
- Primary completion
- 2019-08-15
- Completion
- 2019-10-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Isotretinoin | Other / unclassified | 0.5 mg/kg | — |
| Subject | Isotretinoin | Other / unclassified | 1 mg/kg | — |