drugset / Trial / NCT04205656
Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction
Phase 1/2
Active not recruiting
45 enrolled
Steadman Philippon Research Institute
Office of Naval Research (ONR) · collabUnited States Department of Defense · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
This is a prospective, randomized, placebo-controlled trial to evaluate potential beneficial effects of leukocyte-poor platelet rich plasma and bone marrow concentrate on the healing and health of critical joint tissues in the knee following anterior cruciate ligament (ACL) reconstruction. Bone marrow contains stem cells which can change into cells of various different tissue types, while platelet rich plasma contains growth factors. This trial will compare the two procedures against placebo.
Timeline
- Start
- 2020-01-02
- Primary completion
- 2024-07
- Completion
- 2024-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bone Marrow Concentrate | Cell therapy | — | — |
| Subject | Platelet Rich Plasma | Other / unclassified | — | Other |