Use of Curcumin to Treat Unfavorable Bleeding Patterns in Contraceptive Implant Users

Summary

The investigators plan to study the effects of curcumin, the active ingredient in the spice turmeric, on the irregular bleeding experienced by women who use the contraceptive implant.

Timeline

Start

2020-04-15

Primary completion

2022-11-05

Completion

2023-08-01

Outcome

Missed primary endpoint

paper Daily use of curcumin did not improve bleeding patterns in users of the etonogestrel contraceptive implant experiencing frequent or prolonged bleeding patterns. PMID 37116825 ↗

Publications

• Edelman A, Boniface E, Schrote K, Messerle-Forbes M, O'Donnell A, Jensen JT, Han L. Treatment of unfavorable bleeding patterns in contraceptive implant users: a randomized clinical trial of curcumin. Am J Obstet Gynecol. 2023 Aug;229(2):145.e1-145.e9. doi: 10.1016/j.ajog.2023.04.028. Epub 2023 Apr 26.

Drugs

Indications