drugset / Trial / NCT04207112

Summary

The current treatment regimen for MDR-TB has poor outcomes and costs of treating MDR-TB are greater than treating drug susceptible TB, both in terms of health service and patient-incurred costs. Urgent action is needed to Identify short, effective and tolerable treatments for people with MDR-TB. The PRACTECAL economic evaluation sub-study (PRACTECAL-EE) will take place alongside the TB PRACTECAL trial, aiming to assess the costs to patients and providers of such regimens and to estimate the cost-effectiveness and poverty impact of an introduction of new MDR-TB regimens in the three countries participating in the main study.

Timeline

Start
2020-10-20
Primary completion
2022-08-25
Completion
2022-08-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Bedaquiline Small molecule 200 mg
Subject Clofazimine Small molecule 50 mg
Subject Clofazimine Small molecule 100 mg
Subject Linezolid Other / unclassified 300 mg
Subject Linezolid Other / unclassified 600 mg
Subject Moxifloxacin Small molecule 400 mg
Subject Pretomanid Small molecule 200 mg