drugset / Trial / NCT04207385

Accurate Clinical Study of Medication in Patients With Depression Via Pharmacogenomics (PGx) and Therapeutic Drug Monitoring (TDM) of Venlafaxine

NCT04207385

Phase 4 Unknown 160 enrolled Xijing Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

This study evaluates the efficacy of PGx-guided medication in patients with depression treated with Venlafaxine and the efficacy of the combination of PGx and TDM in patients with depression treated with Venlafaxine. Half of participants will receive PGx-guided treatment, while the other half will receive routine treatment. After the 8th week, the PGx-guided treatment group would be randomly divided into two groups. Of which, half of participants will receive the combination of PGx and TDM, and the other half will receive PGx -guided medication only.

Timeline

Start
2019-12-01
Primary completion
2021-08-31
Completion
2021-11-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Venlafaxine Small molecule 75 mg
Subject Venlafaxine Small molecule 225 mg

Indications