drugset / Trial / NCT04207918

A Phase II Study of Chemoradiotherapy With Nimotuzumab in Unresectable Esophageal Cancer

NCT04207918

NaSingle-groupOpen-labelTreatment

Summary

This phase II clinical study is designed to evaluate the 1 year local tumor control rates after the targeted therapy of intensity-modulated radiation therapy synchronized chemotherapy with nimotuzumab combined with S-1 in local advanced esophageal squamous cell carcinomas based on Nutritional Risk Screening NRS2002.

Timeline

Start
2019-11-14
Primary completion
2022-12-30
Completion
2023-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Nimotuzumab Monoclonal antibody 400 mg Intravenous
Subject S-1 Small molecule 40 mg/m2 Oral
Subject S-1 Small molecule 60 mg/m2 Oral