drugset / Trial / NCT04211415

Phase I Study of DS-2741a in Healthy Volunteers and Participants With Atopic Dermatitis

NCT04211415 ↗

Phase 1 Terminated 8 enrolled Daiichi Sankyo
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This is a phase 1, single-center, first-in-human study to assess the safety, pharmacokinetics and pharmacodynamics of DS-2741a after subcutaneous injection in healthy Japanese male volunteers and Japanese participants with moderate to severe atopic dermatitis.

Timeline

Start
2020-01-13
Primary completion
2020-03-14
Completion
2020-12-18

Outcome

Outcome not reported

Stopped: “Company decision of termination of the clinical program.”

Drugs

EvaluationDrugModalityDoseRoute
Subject DS-2741a Unknown 5 mg Subcutaneous
Subject DS-2741a Unknown 15 mg Subcutaneous
Subject DS-2741a Unknown 50 mg Subcutaneous
Subject DS-2741a Unknown 150 mg Subcutaneous
Subject DS-2741a Unknown 500 mg Subcutaneous
Subject DS-2741a Unknown 1000 mg Subcutaneous

Indications