drugset / Trial / NCT04211415
Phase I Study of DS-2741a in Healthy Volunteers and Participants With Atopic Dermatitis
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This is a phase 1, single-center, first-in-human study to assess the safety, pharmacokinetics and pharmacodynamics of DS-2741a after subcutaneous injection in healthy Japanese male volunteers and Japanese participants with moderate to severe atopic dermatitis.
Timeline
- Start
- 2020-01-13
- Primary completion
- 2020-03-14
- Completion
- 2020-12-18
Outcome
Outcome not reported
Stopped: “Company decision of termination of the clinical program.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | DS-2741a | Unknown | 5 mg | Subcutaneous |
| Subject | DS-2741a | Unknown | 15 mg | Subcutaneous |
| Subject | DS-2741a | Unknown | 50 mg | Subcutaneous |
| Subject | DS-2741a | Unknown | 150 mg | Subcutaneous |
| Subject | DS-2741a | Unknown | 500 mg | Subcutaneous |
| Subject | DS-2741a | Unknown | 1000 mg | Subcutaneous |