drugset / Trial / NCT04216888

Biomarkers of Response to Ketamine in Depression: MRI and Blood Assays Before and After Open Label Intranasal Ketamine

NCT04216888

Phase 2/3 Completed 9 enrolled Dan Iosifescu
NaSingle-groupOpen-labelBasic science

Summary

This pilot study aims to identify predictors of response to intranasal ketamine treatment in patients with treatment-resistant depression. Participants will give a sample of blood and undergo magnetic resonance imaging before and after a single intranasal ketamine treatment. Participants will subsequently receive a second intranasal ketamine treatment.

Timeline

Start
2019-06-26
Primary completion
2020-12-28
Completion
2020-12-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketamine Small molecule 40 mg Intranasal