Radical Radiotherapy and Chemotherapy Combined With Maintenance Chemotherapy in the Treatment of Stage N3 NPC

Summary

This study is a randomized, phase II, prospective, multicenter clinical trial to evaluate the efficacy and safety of radical chemoradiotherapy plus oral capecitabine/teggio for 1 year in patients with N3.

Timeline

Start

2019-12-01

Primary completion

2023-06-01

Completion

2023-12-01

Publications

• Lin X, Huang L, Zheng J, Chen B, Huang C, Chen L, Pan C, Guo Q, Lin S, Zong J. Efficacy and safety of schedule-modified oral capecitabine/S-1 as maintenance therapy for stage N3 nasopharyngeal carcinoma after definitive chemoradiotherapy: a multicentre, single-arm phase II clinical trial. BMC Oral Health. 2026 Jun 9. doi: 10.1186/s12903-026-08865-8. Online ahead of print.

Drugs

Indications