Efficacy of Diltiazem for the Control of Blood Pressure in Puerperal Patients With Severe Preeclampsia

Summary

Both preeclampsia and eclampsia are important health problems, being an important cause of maternal death in the world. Nifedipine has been used as the drug of choice for the treatment of hypertension during puerperium for more than 25 years. Diltiazem is an alternative calcium antagonist that is 1000 times less potent than nifedipine. There are no reports in the literature, no randomized clinical trials that prove the effectiveness of diltiazem for the control of blood pressure in post-partum patients with severe preeclampsia.

Timeline

Start

2009-01-01

Primary completion

2009-05-30

Completion

2009-05-30

Publications

• Arias-Hernandez G, Vargas-De-Leon C, Calzada-Mendoza CC, Ocharan-Hernandez ME. Efficacy of Diltiazem for the Control of Blood Pressure in Puerperal Patients with Severe Preeclampsia: A Randomized, Single-Blind, Controlled Trial. Int J Hypertens. 2020 Jul 23;2020:5347918. doi: 10.1155/2020/5347918. eCollection 2020.

Drugs

Indications