Investigation of Brain Mechanisms Involved in Urgency Urinary Incontinence

Summary

This is a randomized double-blind crossover trial of trospium and placebo in women with urgency urinary incontinence, with evaluation (history, physical, incontinence evaluation and brain MRI) at baseline, and after each course of therapy. The investigators will evaluate functional brain changes in relation to bladder improvement in order to improve our knowledge of the brain's role in the continence mechanism.

Timeline

Start

2020-02-13

Primary completion

2025-02-28

Completion

2025-10-30

Drugs

Indications