drugset / Trial / NCT04227327

Study Evaluating Abemaciclib + Aromatase Inhibitors in HR+, HER2- Advanced Breast Cancer Patients (HERMIONE-7)

NCT04227327

Phase 2 Terminated 31 enrolled University of Milano Bicocca
NaSingle-groupOpen-labelTreatment

Summary

The HERMIONE-7 trial is a phase II, single-arm, open-label, multicenter study in HR+, HER2- advanced breast cancer patients who have received HD-FUL as first-line endocrine treatment for their metastatic disease. Patients will receive aromatase inhibitors plus Abemaciclib.

Timeline

Start
2020-01-07
Primary completion
2024-07-25
Completion
2024-07-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Abemaciclib Small molecule 150 mg Oral
Subject Anastrozole Other / unclassified 1 mg
Subject Letrozole Other / unclassified 2.5 mg

Indications