drugset / Trial / NCT04231084

Comparison of Vasodilator Response of Inhaled Epoprostenol and Inhaled Nitric Oxide

NCT04231084

Phase 4 Completed 115 enrolled Brigham and Women's Hospital
RandomizedCrossoverTriple-blindDiagnostic

Summary

The overarching goal of this study is to examine the acute vasoreactive response to both inhaled nitric oxide and inhaled epoprostenol across both traditionally and non-traditionally interrogated phenotypes in PH, and to further characterize the relationship of vasoreactivity to disease severity and PH phenotype.

Timeline

Start
2021-01-15
Primary completion
2024-08-01
Completion
2024-08-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Nitric Oxide Other / unclassified Inhaled
Subject epoprostenol Other / unclassified Inhaled