A Study to Assess the Effect AZD4831 in Japanese and Chinese Healthy Volunteers

Summary

This study is randomized, single-blind, placebo-controlled Phase 1 study aimed to assess the safety and efficacy, pharmacokinetics and pharmacodynamics of multiple doses of oral AZD4831 in healthy Japanese and Chinese volunteers

Timeline

Start

2020-01-16

Primary completion

2021-03-11

Completion

2021-03-11

Publications

• Sunnaker M, Bhattacharya C, Nelander K, Aurell M, Heijer M, Collen A, Han D, Holden J, Trebski M, Garkaviy P, Ericsson H. Pharmacokinetics and Tolerability of the Novel Myeloperoxidase Inhibitor Mitiperstat in Healthy Japanese and Chinese Volunteers. Clin Drug Investig. 2024 Nov;44(11):863-874. doi: 10.1007/s40261-024-01402-x. Epub 2024 Nov 4.

Drugs

Indications