drugset / Trial / NCT04233892

Clinical Study of in Situ Regeneration of Endometrium

NCT04233892

Phase 1/2 Unknown 345 enrolled Yali Hu Chinese Academy of Sciences · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

Thin endometrium will lead to hypomenorrhea,infertility and recurrent pregnancy loss and there are few effective methods to increase the endometrial thickness and improve the fertility outcomes. Patients with thin endometrium will be divided into three groups and receive estrogen therapy, stem cell therapy and growth factor therapy respectively. This randomized controlled clinical study is carried out to explore the optimal treatment method and best indications for thin endometrium.

Timeline

Start
2020-04-29
Primary completion
2022-12
Completion
2024-12

Drugs

EvaluationDrugModalityDoseRoute
Subject CBD-bFGF Protein / enzyme biologic Other
Subject autologous bone marrow mononuclear cells Cell therapy Other