Whitening Efficacy of Dentifrice Containing 10% High Cleaning Silica, 0.5% Sodium Phytate and 0.5% Sodium Pyrophosphate

Completed 86 enrolled Sun Yat-sen University

RandomizedParallel-groupDouble-blindTreatment

Summary

The objective of the present study was to compare the effects of a commercially available dentifrice containing 10% high cleaning silica base, 0.5% sodium phytate and 0.5% sodium pyrophosphate versus a negative control dentifrice on removal of extrinsic stains.

Timeline

Start: 2018-05-07
Primary completion: 2018-09-28
Completion: 2018-10-05

Publications

Liu H, Tu J. Reduction of extrinsic tooth stain by a toothpaste containing 10% high cleaning silica, 0.5% sodium phytate and 0.5% sodium pyrophosphate: an 8-week randomised clinical trial. BMC Oral Health. 2021 Mar 11;21(1):113. doi: 10.1186/s12903-021-01484-5.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	high cleaning silica base	Unknown	10 %	Topical
Subject	phytate	Unknown	0.5 %	Topical
Subject	sodium pyrophosphate	Unknown	0.5 %	Topical

Indications

No indication recorded.