drugset / Trial / NCT04241640

Nefopam for Post Video-Assisted Thoracoscopic Lobectomy

NCT04241640

Phase 4 Completed 72 enrolled Mahidol University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Video-assisted thoracoscopic (VATs) lobectomy is mild to moderately pain procedure. For conventional thoracotomy, there are many invasive pain control such as epidural analgesia, paravertebral block. However, for VATs, the invasive pain control somehow are too invasive. Nefopam is non-opioid painkilling medication, Serotonin, norepinephrine, dopamine reuptake inhibitor. Many study were demonstrated positive outcome of nefopam usage in many operation such as abdominal surgery, laparocopic surgery, orthopedic surgery. Nevertheless, nefopam for VATs is not well studied yet.

Timeline

Start
2020-09-01
Primary completion
2022-08-01
Completion
2023-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Nefopam Small molecule 80 mg

Indications

No indication recorded.