drugset / Trial / NCT04242927
A Study to Investigate Nicotinic Acid on VEGFR Inhibitor-Associated Hand-Foot Skin Reactions
RandomizedParallel-groupQuadruple-blindSupportive care
Summary
Hand-Foot Skin Reaction (HFSR) is a common adverse event induced by Vascular Endothelial Growth Receptor Inhibitor (VEGFRi) in cancer patients. The main purpose of this study is to evaluate the efficacy and safety of nicotinic acid in solid tumor patients with grade II/III VEGFRi-associated HFSR.
Timeline
- Start
- 2020-03-09
- Primary completion
- 2021-03-09
- Completion
- 2022-03-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Niacin | Small molecule | 50 mg | Oral |
| Subject | Niacin | Small molecule | 100 mg | Oral |