Combined Effect of Acitretin and Narrow Band Ultraviolet B on Vitiligo Repigmentation

Summary

Since abnormal keratinocyte (KC) proliferation and differentiation as well as defective E cadherin expression were reported in vitiligo lesions, the investigators set to study the potential efficacy of combining Retinoids, which are known to improve KC proliferation and differentiation and increase the expression of adhesion molecules, with narrowband UVB in the treatment of vitiligo.

Timeline

Start

2020-01-01

Primary completion

2021-11-30

Completion

2021-12-01

Drugs

Indications