drugset / Trial / NCT04246749
Mass Balance and Pharmacokinetics of [14C]-CRN00808 in Healthy Volunteers
Non-randomizedSingle-groupOpen-labelTreatment
Summary
A phase 1 healthy volunteer study to assess the mass balance, elimination, and metabolic profile of CRN00808. The study will be conducted in 2 parts: Part A, to characterize the absorption, distribution, metabolism, excretion, and mass balance of orally administered radio-labeled CRN00808; Part B, to determine the absolute bioavailability of CRN00808 administered using CRN00808 and radio-labeled CRN00808 as intravenous and oral forms.
Timeline
- Start
- 2019-09-17
- Primary completion
- 2019-10-25
- Completion
- 2019-10-25
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Paltusotine | Small molecule | — | Oral |
Indications
No indication recorded.