drugset / Trial / NCT04247815
Study of ATI-450 Plus Methotrexate (MTX) vs MTX Alone in Patients With Moderate to Severe RA
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This is a Phase 2 study to investigate the safety, tolerability, PK, and PD of ATI-450 plus methotrexate versus methotrexate alone in patients with moderate to severe RA.
Timeline
- Start
- 2020-03-16
- Primary completion
- 2021-02-04
- Completion
- 2021-02-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Zunsemetinib | Small molecule | 50 mg | Oral |
| Background | Methotrexate | Small molecule | 7.5 mg | — |
| Background | Methotrexate | Small molecule | 25 mg | — |