drugset / Trial / NCT04250506
A Study to Assess the Effect of Single Doses of Daridorexant on Electrocardiogram Parameters in Healthy Subjects
RandomizedCrossoverQuadruple-blindOther
Summary
A study to assess the effect of single doses of daridorexant on electrocardiogram parameters in healthy subjects
Timeline
- Start
- 2020-02-28
- Primary completion
- 2020-07-22
- Completion
- 2020-07-22
Outcome
Met primary endpoint
paper the upper bounds of the CIs were < 10 ms defined as threshold of regulatory concern. PMID 34331678 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Daridorexant | Small molecule | 50 mg | Oral |
| Subject | Daridorexant | Small molecule | 200 mg | Oral |
| Comparator | Moxifloxacin | Small molecule | 400 mg | Oral |
Indications
No indication recorded.