drugset / Trial / NCT04256603

Evaluation of Initiation Time on the Efficacy of Gabapentin in Treating Neuropathic Pain in SCI

NCT04256603

Phase 4 Completed 27 enrolled MetroHealth Medical Center
Non-randomizedParallel-groupOpen-labelPrevention

Summary

Neuropathic pain is a common complaint in those with spinal cord injury (SCI) that has a significant negative effect on quality of life. Efficacy of various treatments, however, remains controversial. There is evidence to support that gabapentin and pregabalin have some benefit in reducing neuropathic pain. Gabapentin is effective in the management of symptoms and concerns related to SCI including motor recovery, spasticity, and mood among others. This makes gabapentin an important pharmacologic intervention, which compels providers to define treatment guidelines related to its use. One aspect of which should relate to the timing of initiation of therapy. The goal of this study is to determine whether timing of initiation of treatment with gabapentin will decrease prevalence and intensity of neuropathic pain.

Timeline

Start
2019-08-01
Primary completion
2020-03-30
Completion
2020-04-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Gabapentin Small molecule