drugset / Trial / NCT04262765
Drug-drug-interaction Study of Ramipril, Amlodipine and Atorvastatin
NaSingle-groupOpen-labelTreatment
Summary
Study to determine the potential pharmacokinetic interaction of ramipril (and ramiprilat), atorvastatin as atorvastatin calcium trihydrate and amlodipine as amlodipine besilate at steady state after a multiple oral administration and to monitor the safety of the co-administration of these drugs. This study aims to determine if the steady state study pharmacokinetic parameters of any of the given drugs and the tolerability is altered when administered concomitantly.
Timeline
- Start
- 2019-02-23
- Primary completion
- 2019-03-26
- Completion
- 2019-03-26
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Amlodipine | Other / unclassified | — | Oral |
| Subject | Atorvastatin | Small molecule | — | Oral |
| Subject | Ramipril | Small molecule | — | Oral |
Indications
No indication recorded.