drugset / Trial / NCT04274595

Role of Reverse Transcriptase Inhibitors in the Treatment of Psoriasis

NCT04274595

Completed 8 enrolled Nîmes University Hospital
NaSingle-groupOpen-labelTreatment

Summary

The investigators hypothesize that the inhibition of endogenous reverse transcriptase would: (1) reduce excess cytosolic DNA, stress initiating the inflammatory loop at the origin of psoriatic lesions, and (2) interrupt the loop and lighten lesions

Timeline

Start
2020-02-13
Primary completion
2021-11-29
Completion
2022-06-20

Drugs

EvaluationDrugModalityDoseRoute
Subject emtricitabine Other / unclassified 200 mg
Subject tenofovir diisopropyl fumarate Unknown 245 mg

Indications