drugset / Trial / NCT04274595
Role of Reverse Transcriptase Inhibitors in the Treatment of Psoriasis
NaSingle-groupOpen-labelTreatment
Summary
The investigators hypothesize that the inhibition of endogenous reverse transcriptase would: (1) reduce excess cytosolic DNA, stress initiating the inflammatory loop at the origin of psoriatic lesions, and (2) interrupt the loop and lighten lesions
Timeline
- Start
- 2020-02-13
- Primary completion
- 2021-11-29
- Completion
- 2022-06-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | emtricitabine | Other / unclassified | 200 mg | — |
| Subject | tenofovir diisopropyl fumarate | Unknown | 245 mg | — |