drugset / Trial / NCT04276480

Efficacy of Piperacillin-tazobactam as Empirical Antimicrobial Therapy for VAP Among ESBL-E Carriers.

NCT04276480

Completed 9 enrolled University Hospital, Bordeaux
NaSingle-groupOpen-labelTreatment

Summary

Antimicrobial resistance is a major threat worldwide and now concerns last-ressource antibiotics such as carbapenems. As the resistance to carbapenems is directly due to their use, their spare has become a public health emergency. Their efficacy in ventilator-associated pneumonia has never been compared to other classes of antibiotics such as piperacillin-tazobactam which can be an alternative to carbapenems.

Timeline

Start
2022-02-16
Primary completion
2024-04-22
Completion
2024-04-22

Drugs

EvaluationDrugModalityDoseRoute
Subject Amoxicillin Other / unclassified 16 g