Orphan Indications for CD19 Redirected Autologous T Cells

Summary

This is an open-label, four-cohort, phase 2 study to determine the efficacy of CART19 in pediatric and young adult patientswith hypodiploid (Cohort A) or t(17;19) B-ALL (Cohort B), infants with very high risk KMT2A B-ALL (Cohort C), and in patients with central nervous system (CNS) relapse who did not receive cranial radiation (XRT) or bone marrow transplantation (BMT) (Cohort D).

Timeline

Start

2020-03-12

Primary completion

2028-03-10

Completion

2037-03-10

Drugs

Indications