drugset / Trial / NCT04277663

The Study of IBI310 in Combination With IBI308 Compared to High-Dose Interferon In Patients With Acral Melanoma That Has Been Removed by Surgery

NCT04277663

Phase 3 Terminated 136 enrolled Innovent Biologics (Suzhou) Co. Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a phase III randomized, control, multi-center study of recombinant humanized anti-PD-1 mAb in combination with CTLA4 mAb for injection compared to high-Dose interferon in patients with acral melanoma that has been removed by surgery.

Timeline

Start
2020-04-17
Primary completion
2023-02-28
Completion
2023-02-28

Drugs

EvaluationDrugModalityDoseRoute
Subject IBI310 Monoclonal antibody 3 mg/kg Intravenous
Subject Sintilimab Monoclonal antibody 200 mg Intravenous
Comparator recombinant interferon a-2B Protein / enzyme biologic 9e+09 iu Intravenous