Prophylactic Effects of Psilocybin on Chronic Cluster Headache

Summary

The purpose of this study is to investigate the prophylactic effects of psilocybin in chronic cluster headache. Subjects will receive a low dose of psilocybin during 3 sessions spaced by one week. Subjects will maintain a headache diary prior to, during, and after the administrations in order to document headache frequency, intensity and duration. Subjects will undergo a fMRI scanning before the first and after the last psilocybin session.

Timeline

Start

2020-01-21

Primary completion

2020-11-01

Completion

2022-06-01

Drugs

Indications