drugset / Trial / NCT04290104
Is an Antibiotic Prescription Required After Laparoscopic Cholecystectomy
RandomizedParallel-groupDouble-blindTreatment
Summary
The need for antibiotics to reduce surgical site infection after cholecystectomy for acute calculous cholecystitis is still controversial. The researchers aimed to investigate the effect of antibiotics prescribed on surgical site infection when discharged to patients undergoing laparoscopic cholecystectomy for acute calculous cholecystitis.
Timeline
- Start
- 2020-10-15
- Primary completion
- 2020-11-30
- Completion
- 2020-12-31
Publications
- Background Magill SS, Edwards JR, Fridkin SK; Emerging Infections Program Healthcare-Associated Infections and Antimicrobial Use Prevalence Survey Team. Survey of health care-associated infections. N Engl J Med. 2014 Jun 26;370(26):2542-3. doi: 10.1056/NEJMc1405194. No abstract available.
- Background Duncan CB, Riall TS. Evidence-based current surgical practice: calculous gallbladder disease. J Gastrointest Surg. 2012 Nov;16(11):2011-25. doi: 10.1007/s11605-012-2024-1. Epub 2012 Sep 18.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ampicillin | Unknown | — | Oral |
| Subject | Sulbactam | Small molecule | — | Oral |