drugset / Trial / NCT04291118

Assessing Improvement in Cognitive Deficit in CRS in Patients Treated With Medical Vs Surgical Management

NCT04291118

Unknown 150 enrolled St. Paul's Hospital, Canada
Non-randomizedParallel-groupOpen-labelOther

Summary

Chronic rhinosinusitis presents with a plethora of symptoms including non-rhinologic symptoms such as depression, sleep disturbances \& the more recently recognized cognitive dysfunction. It has recently been identified that sinus specific treatments such as endoscopic sinus surgery can improve cognitive outcomes in patients with cognitive deficit secondary to chronic inflammation in the upper and lower airway. However, it remains to be seen whether or not offering surgery to these patients at an earlier date has an impact on the degree of improvement on cognitive function in comparison to patients who have to wait long periods for their treatment.

Timeline

Start
2020-02-10
Primary completion
2021-09-01
Completion
2021-10-01

Drugs

EvaluationDrugModalityDoseRoute
Background Budesonide Small molecule Intranasal