drugset / Trial / NCT04293042
Treatment of BK Virus Infection With CTL Cells in Immunocompromised Transplant Patients
NaSingle-groupOpen-labelSupportive care
Summary
This is a pilot study using cytotoxic T lymphocytes (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Gamma-capture system will be effective in decreasing specific viral load in patients with BK virus viremia and BK virus-associated symptoms post-allogeneic hematopoietic stem cell transplantation (HSCT), renal transplantation, and chemotherapy.
Timeline
- Start
- 2019-10-07
- Primary completion
- 2028-01-30
- Completion
- 2029-01-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | BK-virus specific CTLs | Cell therapy | 5000 cells/kg | Intravenous |
| Subject | BK-virus specific CTLs | Cell therapy | 25000 cells/kg | Intravenous |