drugset / Trial / NCT04306315

Adjusted Brodalumab Dose Compared With Standard Brodalumab Dose in Subjects With Moderate-to-severe Plaque Psoriasis and ≥120 kg Body Weight

NCT04306315

Phase 4 Completed 385 enrolled LEO Pharma
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study investigates if an adjusted brodalumab dosage regimen will give improved efficacy in psoriasis in patients with a body weight of over 120 kg. The increased dosage regimen will be compared to the standard brodalumab treatment plus placebo.

Timeline

Start
2022-07-21
Primary completion
2025-08-25
Completion
2026-01-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Brodalumab Monoclonal antibody 210 mg
Subject Brodalumab Monoclonal antibody 280 mg

Indications