drugset / Trial / NCT04306315
Adjusted Brodalumab Dose Compared With Standard Brodalumab Dose in Subjects With Moderate-to-severe Plaque Psoriasis and ≥120 kg Body Weight
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This study investigates if an adjusted brodalumab dosage regimen will give improved efficacy in psoriasis in patients with a body weight of over 120 kg. The increased dosage regimen will be compared to the standard brodalumab treatment plus placebo.
Timeline
- Start
- 2022-07-21
- Primary completion
- 2025-08-25
- Completion
- 2026-01-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Brodalumab | Monoclonal antibody | 210 mg | — |
| Subject | Brodalumab | Monoclonal antibody | 280 mg | — |