drugset / Trial / NCT04306627

Effect of Atorvastatin on Carotid Intima Media Thickness

NCT04306627

RandomizedParallel-groupOpen-labelTreatment

Summary

The investigators hypothesize that additive effects of combined antihypertensive medications and statin in a single pill combination may better reduce progression of vascular remodeling and inhibit atherosclerosis progression. The fixed association of atorvastatin, perindopril and amlodipine under the name of Lipertance is the first fixed combination of these three groups to control the risk factors that are hypertension and dyslipidemia which can be used both in primary and secondary cardiovascular prevention .

Timeline

Start
2020-04-15
Primary completion
2020-10-16
Completion
2021-02-28

Drugs

EvaluationDrugModalityDoseRoute
Comparator Amlodipine Other / unclassified
Comparator Atorvastatin Small molecule
Comparator Perindopril Small molecule