drugset / Trial / NCT04306627
Effect of Atorvastatin on Carotid Intima Media Thickness
RandomizedParallel-groupOpen-labelTreatment
Summary
The investigators hypothesize that additive effects of combined antihypertensive medications and statin in a single pill combination may better reduce progression of vascular remodeling and inhibit atherosclerosis progression. The fixed association of atorvastatin, perindopril and amlodipine under the name of Lipertance is the first fixed combination of these three groups to control the risk factors that are hypertension and dyslipidemia which can be used both in primary and secondary cardiovascular prevention .
Timeline
- Start
- 2020-04-15
- Primary completion
- 2020-10-16
- Completion
- 2021-02-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amlodipine | Other / unclassified | — | — |
| Comparator | Atorvastatin | Small molecule | — | — |
| Comparator | Perindopril | Small molecule | — | — |