drugset / Trial / NCT04315181
Prescription Medication Interactions
RandomizedCrossoverDouble-blindBasic science
Summary
This study will examine the effects of doses of opioid/placebo and doses of sedative/placebo, alone and in combination. The primary outcomes are related to pharmacodynamic measures (subjective ratings of drug liking and other abuse-related effects; physiological outcomes) to determine the interaction effects of these compounds.
Timeline
- Start
- 2019-03-25
- Primary completion
- 2023-05-06
- Completion
- 2023-05-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Gabapentin | Small molecule | 600 mg | Oral |
| Subject | Gabapentin | Small molecule | 1200 mg | Oral |
| Subject | Oxycodone | Other / unclassified | 20 mg | Oral |
| Subject | Oxycodone | Other / unclassified | 40 mg | Oral |