drugset / Trial / NCT04318717

Pembrolizumab and Hypofractionated Radiation Therapy for the Treatment of Mucosal Melanoma

NCT04318717 ↗

Phase 2 Recruiting 20 enrolled Washington University School of Medicine
NaSingle-groupOpen-labelTreatment

Summary

This is an open-label, single center, one cohort, non-randomized, phase II study. The aim is to evaluate the efficacy and safety of the combination of hypofractionated radiotherapy (HRT) and pembrolizumab on local tumor control in mucosal melanoma patients. Treatment effect will be compared with historical radiation therapy-alone control data.

Timeline

Start
2020-05-29
Primary completion
2030-07-31
Completion
2032-07-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Pembrolizumab Monoclonal antibody 200 mg Intravenous

Indications