drugset / Trial / NCT04325633
Efficacy of Addition of Naproxen in the Treatment of Critically Ill Patients Hospitalized for COVID-19 Infection
RandomizedParallel-groupOpen-labelTreatment
Summary
The symptoms of respiratory distress caused by COVID-19 may be reduced by drugs combining anti-inflammatory and antiviral effects. This dual effect may simultaneously protect severely-ill patients and reduce the viral load, therefore limiting virus dissemination We want to demonstrate the superiority of naproxen (anti-inflamatory drug) treatment addition to standard of care compared to standard of care in term of 30-day mortality.
Timeline
- Start
- 2020-04-24
- Primary completion
- 2020-12-15
- Completion
- 2020-12-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Naproxen | Small molecule | 250 mg | — |
| Background | Lansoprazole | Other / unclassified | 30 mg | — |