drugset / Trial / NCT04325633

Efficacy of Addition of Naproxen in the Treatment of Critically Ill Patients Hospitalized for COVID-19 Infection

NCT04325633

Phase 3 Terminated 30 enrolled Assistance Publique - Hôpitaux de Paris
RandomizedParallel-groupOpen-labelTreatment

Summary

The symptoms of respiratory distress caused by COVID-19 may be reduced by drugs combining anti-inflammatory and antiviral effects. This dual effect may simultaneously protect severely-ill patients and reduce the viral load, therefore limiting virus dissemination We want to demonstrate the superiority of naproxen (anti-inflamatory drug) treatment addition to standard of care compared to standard of care in term of 30-day mortality.

Timeline

Start
2020-04-24
Primary completion
2020-12-15
Completion
2020-12-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Naproxen Small molecule 250 mg
Background Lansoprazole Other / unclassified 30 mg

Indications