drugset / Trial / NCT04325685

The Effect of Supraglottic and Oropharyngeal Decontamination on the Incidence of Ventilator-associated Pneumonia

NCT04325685

Completed 60 enrolled Northern State Medical University
RandomizedParallel-groupSingle-blindPrevention

Summary

Oropharynx is the main source of pathogen microorganisms for the ventilator - associated pneumoniae. As known bacteriophages can eliminate different pathogen microorganisms or reduce a degree of a pathogen's colonization. The research team is considering that oropharyngeal decontamination with bacteriophages can prevent the developing of the ventilator - associated pneumoniae. There will be three groups in this investigation: placebo, antiseptic drug (Octenisept) and bacteriophage (Sexthaphag).

Timeline

Start
2020-01-01
Primary completion
2021-12-31
Completion
2023-11-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Bacteriophage Other / unclassified Other
Comparator Octenisept Unknown Other