drugset / Trial / NCT04325776

A Study of AL2846 Versus Zoledronic Acid in Subjects With Advanced Non-Small Cell Lung Cancer With Bone Metastasis

NCT04325776

RandomizedParallel-groupQuadruple-blindTreatment

Summary

AL2846 is a multi-target tyrosine kinase receptor inhibitor with obvious selective to c-met, suggesting that its anti-tumor effect mainly inhibits the activation of key downstream oncogenic pathways by inhibiting expression of c-met, tumor angiogenesis and tumor cell migration.

Timeline

Start
2020-09-24
Primary completion
2021-05
Completion
2021-11

Drugs

EvaluationDrugModalityDoseRoute
Subject AL2846 Small molecule 150 mg Oral
Comparator Zoledronic acid Other / unclassified 4 mg Intravenous