drugset / Trial / NCT04325802
Treatment of Chronic Itch in Atopic Dermatitis With Opioid Antagonist Naltrexone
RandomizedCrossoverQuadruple-blindTreatment
Summary
Purpose: To study the etiology and the epigenetic pathways leading to and regulating chronic itch. Similarly, to examine the mechanisms underlying skin changes, including epigenetic alterations while also testing the efficacy of opioid antagonists in atopic dermatitis. In this study, the investigators aim to examine chronic sensory disorder mechanisms related to chronic itch.
Timeline
- Start
- 2022-12-31
- Primary completion
- 2024-06
- Completion
- 2024-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Naltrexone | Small molecule | 50 mg | — |