drugset / Trial / NCT04325880

Efficacy of Mirabegron Versus Tamsulosin Versus Solifenacin for Treatment of Ureteral Stents-Related Symptoms

NCT04325880

Phase 3 Unknown 240 enrolled Mansoura University
RandomizedParallel-groupDouble-blindTreatment

Summary

The primary objective of this prospective, single-centre randomized controlled trial is to assess the efficacy of three different drugs in treatment of ureteral stents related symptoms (Beta 3 adrenergic receptor agonist; Mirabegron 50mg) vs. (Alpha 1 adrenergic receptor antagonist; Tamsulosin 0.4mg) vs. (Anticholinergic; Solifenacin 10 mg) using validated symptoms questionnaires. In addition, adverse events of the utilized medications will be monitored during study period as a secondary objective.

Timeline

Start
2021-12-01
Primary completion
2022-06-01
Completion
2022-07-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Mirabegron Other / unclassified 50 mg
Comparator Solifenacin Small molecule 10 mg
Comparator Tamsulosin Other / unclassified 0.4 mg

Indications