drugset / Trial / NCT04325880
Efficacy of Mirabegron Versus Tamsulosin Versus Solifenacin for Treatment of Ureteral Stents-Related Symptoms
RandomizedParallel-groupDouble-blindTreatment
Summary
The primary objective of this prospective, single-centre randomized controlled trial is to assess the efficacy of three different drugs in treatment of ureteral stents related symptoms (Beta 3 adrenergic receptor agonist; Mirabegron 50mg) vs. (Alpha 1 adrenergic receptor antagonist; Tamsulosin 0.4mg) vs. (Anticholinergic; Solifenacin 10 mg) using validated symptoms questionnaires. In addition, adverse events of the utilized medications will be monitored during study period as a secondary objective.
Timeline
- Start
- 2021-12-01
- Primary completion
- 2022-06-01
- Completion
- 2022-07-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Mirabegron | Other / unclassified | 50 mg | — |
| Comparator | Solifenacin | Small molecule | 10 mg | — |
| Comparator | Tamsulosin | Other / unclassified | 0.4 mg | — |