drugset / Trial / NCT04326478
Single Dose Azithromycin to Prevent Cholera in Children
Phase 2
Active not recruiting
920 enrolled
Massachusetts General Hospital
International Centre for Diarrhoeal Disease Research, Bangladesh · collab
RandomizedParallel-groupQuadruple-blindPrevention
Summary
This study aims to determine whether single-dose azithromycin is effective in preventing cholera in children who are at extremely high risk of infection. The study will also determine the effect of this intervention on the development of antibiotic resistant bacteria. The results will inform future strategies to prevent cholera in children, and improve overall understanding of the impact of azithromycin on antibiotic resistance.
Timeline
- Start
- 2021-10-31
- Primary completion
- 2025-05-31
- Completion
- 2026-05-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Azithromycin | Small molecule | 20 mg/kg | — |