MIRs 04 : Interpectoral Nerve Block With Ropivacaine Versus Placebo Before Breast Cancer Surgery

Phase 3 Completed 182 enrolled Institut Curie

RandomizedParallel-groupDouble-blindTreatment

Summary

Compare the effect of ropivacaine versus placebo pectoral nerve block (Pecs 1 and 2) on acute pain after tumorectomy plus sentinel lymph node dissection on one day surgery.

Timeline

Start: 2020-08-04
Primary completion: 2021-12-30
Completion: 2022-01-28

Outcome

Met primary endpoint

paper The analgesic rescue incidence was lower in the ropivacaine group. PMID 40068583 ↗

Publications

Results Albi-Feldzer A, Gayraud G, Dureau S, Auge M, Lemoine A, Raft J. Efficiency of interpectoral and pectoserratus plane blocks for breast surgery: A randomized controlled trial. J Clin Anesth. 2025 Apr;103:111805. doi: 10.1016/j.jclinane.2025.111805. Epub 2025 Mar 10.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ropivacaine	Other / unclassified	5 mg/ml	Other