drugset / Trial / NCT04339400

A Study of TQ05105 Tablets in Subjects With Myeloproliferative Neoplasms

NCT04339400

Phase 1 Completed 79 enrolled Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NaSingle-groupOpen-labelTreatment

Summary

TQ05105 is a JAK2 inhibitors and can be used to treat JAK2 target-related diseases. The activation of the JAK/STAT pathway is related to abnormal proliferation, obstruction of apoptosis, and differentiation disorder of leukemia cells which is caused by genetic abnormalities and viral infection.

Timeline

Start
2018-11-20
Primary completion
2023-03-17
Completion
2023-03-17

Drugs

EvaluationDrugModalityDoseRoute
Subject TQ05105 Small molecule 5 mg Oral