drugset / Trial / NCT04341831

Does Teicoplanin Powder Use In Lumbar Instrumentation Surgery Reduce Surgical Site Infection

NCT04341831

Phase 3 Unknown 120 enrolled Bezmialem Vakif University
RandomizedParallel-groupDouble-blindPrevention

Summary

Infection after spinal surgery is one of the serious complications. Spinal surgery infection can cause high morbidity, mortality, and costs. In spite of different prophylactic methods, up to 15% of infection appears after spinal surgery. Vancomycin powder, which is one of the most applied methods, seems to be effective and inexpensive. However, vancomycin administration may be inconvenient in elderly participants with high comorbidity and especially kidney problems. The investigators aimed to reduce the rate of infection in the post-op 90-day period by adding per-op Teicoplanin powder onto the implant in participants scheduled for lumbar posterior instrumentation.

Timeline

Start
2020-04-15
Primary completion
2021-01-15
Completion
2021-04-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Teicoplanin Other / unclassified 200 mg Topical