Comparing Efficacy of 14-day Therapy Doxycycline With Bismuth Subsalicylate Versus Levofloxacin With Tinadizole on Treatment Helicobacter Pylori

Phase 4 Completed 78 enrolled Damascus Hospital

RandomizedParallel-groupSingle-blindTreatment

Summary

Comparison Efficacy of 10-days Therapy with Doxycycline with Bismuth Subsalicylate Versus Levofloxacine with Tinadizole on Eradication of Helicobacter Pylori in Syrian population.

Timeline

Start: 2019-02-01
Primary completion: 2020-08-30
Completion: 2020-09-01

Publications

Alhalabi M, Alassi MW, Alaa Eddin K, Cheha K. Efficacy of two-week therapy with doxycycline-based quadruple regimen versus levofloxacin concomitant regimen for helicobacter pylori infection: a prospective single-center randomized controlled trial. BMC Infect Dis. 2021 Jul 4;21(1):642. doi: 10.1186/s12879-021-06356-5.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Amoxicillin	Other / unclassified	1000 mg	—
Subject	Bismuth subsalicylate	Small molecule	524 mg	—
Subject	Doxycycline	Small molecule	100 mg	—
Comparator	Levofloxacin	Small molecule	500 mg	—
Background	Esomeprazole	Small molecule	20 mg	—
Background	tinidazole	Small molecule	500 mg	—

Comparing Efficacy of 14-day Therapy Doxycycline With Bismuth Subsalicylate Versus Levofloxacin With Tinadizole on Treatment Helicobacter Pylori

Summary

Timeline

Publications

Drugs

Indications